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Publication DateArticle TitleAuthor(s)
Oct-2015Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiaeReavey, Caitlin T; Hickman, Mark J; Dobi, Krista C; Botstein, David; Winston, Fred
12-May-2015Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporterGibney, Patrick A; Schieler, Ariel; Chen, Jonathan C; Rabinowitz, Joshua D; Botstein, David
Aug-2012Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathwayPetti, Allegra A; McIsaac, R Scott; Ho-Shing, Olivia; Bussemaker, Harmen J; Botstein, David
Apr-2018Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast.Gibney, Patrick A; Schieler, Ariel; Chen, Jonathan C; Bacha-Hummel, Jessie M; Botstein, Maxim; et al
15-May-2012A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotesSlavov, Nikolai; Airoldi, Edoardo M; van Oudenaarden, Alexander; Botstein, David
Nov-2011Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeastHickman, Mark J; Petti, Allegra A; Ho-Shing, Olivia; Silverman, Sanford J; McIsaac, R Scott; et al
15-Jan-2013Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expressionSlavov, Nikolai; Botstein, David
Dec-2013Extensive regulation of metabolism and growth during the cell division cycleSlavov, Nikolai; Botstein, David; Caudy, Amy
15-Nov-2011Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiaeMcIsaac, R Scott; Silverman, Sanford J; McClean, Megan N; Gibney, Patrick A; Macinskas, Joanna; et al
Apr-2013Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian CaseReisser, Cyrielle; Dick, Cynthia; Kruglyak, Leonid; Botstein, David; Schacherer, Joseph; et al
2016Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic CellsMøller, Henrik D; Bojsen, Rasmus K; Tachibana, Chris; Parsons, Lance; Botstein, David; et al
Aug-2012Loss of a 20S Proteasome Activator in Saccharomyces cerevisiae Downregulates Genes Important for Genomic Integrity, Increases DNA Damage, and Selectively Sensitizes Cells to Agents With Diverse Mechanisms of ActionDoherty, Kevin M; Pride, Leah D; Lukose, James; Snydsman, Brian E; Charles, Ronald; et al
Jan-2019Minor Isozymes Tailor Yeast Metabolism to Carbon Availability.Bradley, Patrick H; Gibney, Patrick A; Botstein, David; Troyanskaya, Olga G; Rabinowitz, Joshua D
Aug-2012Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathwayMcIsaac, R Scott; Petti, Allegra A; Bussemaker, Harmen J; Botstein, David
Aug-2013Phylogenetic Portrait of the Saccharomyces cerevisiae Functional GenomeGibney, Patrick A; Hickman, Mark J; Bradley, Patrick H; Matese, John C; Botstein, David
2013Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based ReportersMcIsaac, R Scott; Oakes, Benjamin L; Botstein, David; Noyes, Marcus B
Apr-2014Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiaeMcIsaac, R Scott; Gibney, Patrick A; Chandran, Sunil S; Benjamin, Kirsten R; Botstein, David
Feb-2013Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeastMcIsaac, R Scott; Oakes, Benjamin L; Wang, Xin; Dummit, Krysta A; Botstein, David; et al
22-Sep-2011A Test of the Coordinated Expression Hypothesis for the Origin and Maintenance of the GAL Cluster in YeastLang, Gregory I; Botstein, David
15-Jan-2013TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiaeWelch, Aaron Z; Gibney, Patrick A; Botstein, David; Koshland, Douglas E