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|Abstract:||In the mid-1990's, the common poultry pathogen Mycoplasma gallisepticum (MG) made a successful species jump to the eastern North American house finch Haemorhous mexicanus (HM). Subsequent strain diversification allows us to directly quantify, in an experimental setting, the transmission dynamics of three sequentially emergent geographic isolates of MG, which differ in the levels of pathogen load they induce. We find significant among-strain variation in rates of transmission as well as recovery. Pathogen strains also differ in their induction of host morbidity, measured as the severity of eye lesions due to infection. Relationships between pathogen traits are also investigated, with transmission and recovery rates being significantly negatively correlated, while transmission and virulence, measured as average eye lesion score over the course of infection, are positively correlated. By quantifying these disease-relevant parameters and their relationships, we provide the first analysis of the tradeoffs that shape the evolution of this important emerging pathogen.|
|Electronic Publication Date:||18-Apr-2014|
|Citation:||Williams, PD, Dobson, AP, Dhondt, KV, Hawley, DM, Dhondt, AA. (2014). Evidence of trade-offs shaping virulence evolution in an emerging wildlife pathogen. Journal of Evolutionary Biology, 27 (6), 1271 - 1278. doi:10.1111/jeb.12379|
|Pages:||1271 - 1278|
|Type of Material:||Journal Article|
|Journal/Proceeding Title:||Journal of Evolutionary Biology|
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