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What Is a Genome?

Author(s): Goldman, Aaron David; Landweber, Laura F

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Abstract: The genome is often described as the information repository of an organism. Whether millions or billions of letters of DNA, its transmission across generations confers the principal medium for inheritance of organismal traits. Several emerging areas of research demonstrate that this definition is an oversimplification. Here, we explore ways in which a deeper understanding of genomic diversity and cell physiology is challenging the concepts of physical permanence attached to the genome as well as its role as the sole information source for an organism.
Publication Date: 21-Jul-2016
Electronic Publication Date: 21-Jul-2016
Citation: Goldman, Aaron David, Landweber, Laura F. (2016). What Is a Genome?. PLOS Genetics, 12 (7), e1006181 - e1006181. doi:10.1371/journal.pgen.1006181
DOI: doi:10.1371/journal.pgen.1006181
EISSN: 1553-7404
Pages: e1006181
Type of Material: Journal Article
Journal/Proceeding Title: PLOS Genetics
Version: Final published version. This is an open access article.

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