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Abstract: | High-throughput experimental technologies are generating increasingly massive and complex genomic data sets. The sheer enormity and heterogeneity of these data threaten to make the arising problems computationally infeasible. Fortunately, powerful algorithmic techniques lead to software that can answer important biomedical questions in practice. In this Review, we sample the algorithmic landscape, focusing on state-of-the-art techniques, the understanding of which will aid the bench biologist in analysing omics data. We spotlight specific examples that have facilitated and enriched analyses of sequence, transcriptomic and network data sets. |
Publication Date: | 18-Apr-2013 |
Electronic Publication Date: | 18-Apr-2013 |
Citation: | Berger, B, Peng, J, Singh, M. (2013). Computational solutions for omics data. Nature Reviews Genetics, 14 (333 - 346. doi:10.1038/nrg3433 |
DOI: | doi:10.1038/nrg3433 |
Pages: | 333 - 346 |
Type of Material: | Journal Article |
Journal/Proceeding Title: | Nature Reviews Genetics |
Version: | Author's manuscript |
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