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Noninvasive in vivo glucose sensing on human subjects using mid-infrared light

Author(s): Liakat, S; Bors, KA; Xu, L; Woods, CM; Doyle, J; et al

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dc.contributor.authorLiakat, S-
dc.contributor.authorBors, KA-
dc.contributor.authorXu, L-
dc.contributor.authorWoods, CM-
dc.contributor.authorDoyle, J-
dc.contributor.authorGmachl, Claire F-
dc.date.accessioned2018-07-20T15:10:11Z-
dc.date.available2018-07-20T15:10:11Z-
dc.date.issued2014-06-23en_US
dc.identifier.citationLiakat, S, Bors, KA, Xu, L, Woods, CM, Doyle, J, Gmachl, CF. (2014). Noninvasive in vivo glucose sensing on human subjects using mid-infrared light. Biomedical Optics Express, 5 (2397 - 2404. doi:10.1364/BOE.5.002397en_US
dc.identifier.urihttp://arks.princeton.edu/ark:/88435/pr1pq3t-
dc.description.abstractMid-infrared quantum cascade laser spectroscopy is used to noninvasively predict blood glucose concentrations of three healthy human subjects in vivo. We utilize a hollow-core fiber based optical setup for light delivery and collection along with a broadly tunable quantum cascade laser to obtain spectra from human subjects and use standard chemo-metric techniques (namely partial least squares regression) for prediction analysis. Throughout a glucose concentration range of 80-160 mg/dL, we achieve clinically accurate predictions 84% of the time, on average. This work opens a new path to a noninvasive in vivo glucose sensor that would benefit the lives of hundreds of millions of diabetics worldwide.en_US
dc.format.extent2397 - 2404en_US
dc.language.isoen_USen_US
dc.relation.ispartofBiomedical Optics Expressen_US
dc.rightsFinal published version. Article is made available in OAR by the publisher's permission or policy.en_US
dc.titleNoninvasive in vivo glucose sensing on human subjects using mid-infrared lighten_US
dc.typeJournal Articleen_US
dc.identifier.doidoi:10.1364/BOE.5.002397-
dc.date.eissued2014-06-23en_US
pu.type.symplectichttp://www.symplectic.co.uk/publications/atom-terms/1.0/journal-articleen_US

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