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In vivo measurement of mid-infrared light scattering from human skin

Author(s): Michel, APM; Liakat, S; Bors, K; Gmachl, Claire F

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Abstract: Two mid-infrared light sources, a broadband source from a Fourier Transform Infrared Spectrometer (FTIR) and a pulsed Quantum Cascade (QC) Laser, are used to measure angle-resolved backscattering in vivo from human skin across a broad spectral range. Scattering profiles measured using the FTIR suggest limited penetration of the light into the skin, with most of the light interacting with the stratum corneum layer of the epidermis. Scattering profiles from the QC laser show modulation patterns with angle suggesting interaction with scattering centers in the skin. The scattering is attributed to interaction of the laser light with components such as collagen fibers and capillaries in the dermis layer of the skin.
Publication Date: 4-Mar-2013
Electronic Publication Date: 4-Mar-2013
Citation: Michel, APM, Liakat, S, Bors, K, Gmachl, CF. (2013). In vivo measurement of mid-infrared light scattering from human skin. Biomedical Optics Express, 4 (520 - 530. doi:10.1364/BOE.4.000520
DOI: doi:10.1364/BOE.4.000520
Pages: 520 - 530
Type of Material: Journal Article
Journal/Proceeding Title: Biomedical Optics Express
Version: Final published version. Article is made available in OAR by the publisher's permission or policy.

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