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Five challenges in evolution and infectious diseases

Author(s): Metcalf, C. Jessica E.; Birger, R.B.; Funk, S.; Kouyos, R.D.; Lloyd-Smith, J.O.; et al

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Abstract: Evolution is a key aspect of the biology of many pathogens, driving processes ranging from immune escape to changes in virulence. Because evolution is inherently subject to feedbacks, and because pathogen evolution plays out at scales ranging from within-host to between-host and beyond, evolutionary questions provide special challenges to the modelling community. In this article, we provide an overview of five challenges in modelling the evolution of pathogens and their hosts, and point to areas for development, focussing in particular on the issue of linking theory and data.
Publication Date: Mar-2015
Citation: Metcalf, C.J.E., Birger, R.B., Funk, S., Kouyos, R.D., Lloyd-Smith, J.O., Jansen, V.A.A. (2015). Five challenges in evolution and infectious diseases. Epidemics, 10 (40 - 44). doi:10.1016/j.epidem.2014.12.003
DOI: doi:10.1016/j.epidem.2014.12.003
ISSN: 1755-4365
Pages: 40 - 44
Type of Material: Journal Article
Journal/Proceeding Title: Epidemics
Version: Final published version. This is an open access article.

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