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Boosting understanding of pertussis outbreaks

Author(s): Grenfell, Bryan T.

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Abstract: A central question in epidemiology is the extent to which vaccines provide indirect protection (herd immunity) to infectious diseases, in addition to directly protecting individuals. Such artificial immunity often matches with the strength of natural protection: Vaccines against infections with strong and long-lasting natural immunity, such as measles, often provide very durable and effective protection against both disease and transmission (1, 2). A more complex picture emerges with pertussis (whooping cough), which is caused by a bacterium, Bordetella pertussis. The disease burden arising from this serious childhood infection is still considerable in countries with low vaccination rates.
Publication Date: 3-May-2011
Electronic Publication Date: 20-Apr-2011
Citation: Grenfell, B.T. (2011). Boosting understanding of pertussis outbreaks. Proceedings of the National Academy of Sciences, 108 (18), 7279 - 7280. doi:10.1073/pnas.1103408108
DOI: doi:10.1073/pnas.1103408108
ISSN: 0027-8424
EISSN: 1091-6490
Pages: 7279 - 7280
Type of Material: Journal Article
Journal/Proceeding Title: Proceedings of the National Academy of Sciences
Version: Final published version. Article is made available in OAR by the publisher's permission or policy.



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