Nickel-catalyzed enantioselective arylation of pyridine
Author(s): Lutz, J. Patrick; Chau, Stephen T.; Doyle, Abigail G.
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Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lutz, J. Patrick | - |
dc.contributor.author | Chau, Stephen T. | - |
dc.contributor.author | Doyle, Abigail G. | - |
dc.date.accessioned | 2020-10-30T19:04:15Z | - |
dc.date.available | 2020-10-30T19:04:15Z | - |
dc.date.issued | 2016-03-08 | en_US |
dc.identifier.citation | Lutz, J. Patrick, Chau, Stephen T., Doyle, Abigail G. (2016). Nickel-catalyzed enantioselective arylation of pyridine. Chemical Science, 7 (7), 4105 - 4109. doi:10.1039/C6SC00702C | en_US |
dc.identifier.issn | 2041-6520 | - |
dc.identifier.uri | http://arks.princeton.edu/ark:/88435/pr1bv5q | - |
dc.description.abstract | We report an enantioselective Ni-catalyzed cross coupling of arylzinc reagents with pyridinium ions formed in situ from pyridine and a chloroformate. This reaction provides enantioenriched 2-aryl-1,2- dihydropyridine products that can be elaborated to numerous piperidine derivatives with little or no loss in ee. This method is notable for its use of pyridine, a feedstock chemical, to build a versatile, chiral heterocycle in a single synthetic step. | en_US |
dc.format.extent | 7, 4105 - 4109 | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Chemical Science | en_US |
dc.rights | Final published version. Article is made available in OAR by the publisher's permission or policy. | en_US |
dc.title | Nickel-catalyzed enantioselective arylation of pyridine | en_US |
dc.type | Journal Article | en_US |
dc.identifier.doi | doi:10.1039/C6SC00702C | - |
dc.date.eissued | 2016 | en_US |
dc.identifier.eissn | 2041-6539 | - |
pu.type.symplectic | http://www.symplectic.co.uk/publications/atom-terms/1.0/journal-article | en_US |
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