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|Abstract:||Recently tissue specific stem cells from mammals have been isolated, characterized and grown in three-dimensional cultures producing faithful organoids composed of all the cell and tissue types of the organ . In all cases of diverse tissue specific stem cells the WNT signal transduction pathway functions to promote replication of the stem cells and is regulated by R-spondins acting upon G-linked receptors, LGR 4, 5 and 6, which prove to be excellent biomarkers for these stem cells [1).|
|Electronic Publication Date:||7-Jul-2015|
|Citation:||Levine, Arnold J. (2015). Stem cells, aging and cancers. Aging, 7 (7), 457 - 458. doi:10.18632/aging.100776|
|Pages:||457 - 458|
|Type of Material:||Journal Article|
|Version:||Final published version. This is an open access article.|
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