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http://arks.princeton.edu/ark:/88435/pr13f65| Abstract: | Recently tissue specific stem cells from mammals have been isolated, characterized and grown in three-dimensional cultures producing faithful organoids composed of all the cell and tissue types of the organ [1]. In all cases of diverse tissue specific stem cells the WNT signal transduction pathway functions to promote replication of the stem cells and is regulated by R-spondins acting upon G-linked receptors, LGR 4, 5 and 6, which prove to be excellent biomarkers for these stem cells [1). |
| Publication Date: | 29-Jun-2015 |
| Electronic Publication Date: | 7-Jul-2015 |
| Citation: | Levine, Arnold J. (2015). Stem cells, aging and cancers. Aging, 7 (7), 457 - 458. doi:10.18632/aging.100776 |
| DOI: | doi:10.18632/aging.100776 |
| EISSN: | 1945-4589 |
| Pages: | 457 - 458 |
| Type of Material: | Journal Article |
| Journal/Proceeding Title: | Aging |
| Version: | Final published version. This is an open access article. |
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