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Stem cells, aging and cancers

Author(s): Levine, Arnold J.

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Abstract: Recently tissue specific stem cells from mammals have been isolated, characterized and grown in three-dimensional cultures producing faithful organoids composed of all the cell and tissue types of the organ [1]. In all cases of diverse tissue specific stem cells the WNT signal transduction pathway functions to promote replication of the stem cells and is regulated by R-spondins acting upon G-linked receptors, LGR 4, 5 and 6, which prove to be excellent biomarkers for these stem cells [1).
Publication Date: 29-Jun-2015
Electronic Publication Date: 7-Jul-2015
Citation: Levine, Arnold J. (2015). Stem cells, aging and cancers. Aging, 7 (7), 457 - 458. doi:10.18632/aging.100776
DOI: doi:10.18632/aging.100776
EISSN: 1945-4589
Pages: 457 - 458
Type of Material: Journal Article
Journal/Proceeding Title: Aging
Version: Final published version. This is an open access article.

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