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Stem cells, aging and cancers

Author(s): Levine, Arnold J.

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dc.contributor.authorLevine, Arnold J.-
dc.date.accessioned2020-02-27T18:29:02Z-
dc.date.available2020-02-27T18:29:02Z-
dc.date.issued2015-06-29en_US
dc.identifier.citationLevine, Arnold J. (2015). Stem cells, aging and cancers. Aging, 7 (7), 457 - 458. doi:10.18632/aging.100776en_US
dc.identifier.urihttp://arks.princeton.edu/ark:/88435/pr13f65-
dc.description.abstractRecently tissue specific stem cells from mammals have been isolated, characterized and grown in three-dimensional cultures producing faithful organoids composed of all the cell and tissue types of the organ [1]. In all cases of diverse tissue specific stem cells the WNT signal transduction pathway functions to promote replication of the stem cells and is regulated by R-spondins acting upon G-linked receptors, LGR 4, 5 and 6, which prove to be excellent biomarkers for these stem cells [1).en_US
dc.format.extent457 - 458en_US
dc.language.isoen_USen_US
dc.relation.ispartofAgingen_US
dc.rightsFinal published version. This is an open access article.en_US
dc.titleStem cells, aging and cancersen_US
dc.typeJournal Articleen_US
dc.identifier.doidoi:10.18632/aging.100776-
dc.date.eissued2015-07-07en_US
dc.identifier.eissn1945-4589-
pu.type.symplectichttp://www.symplectic.co.uk/publications/atom-terms/1.0/journal-articleen_US

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