Skip to main content

Ectopic Pregnancy and Emergency Contraceptive Pills - A Systematic Review

Author(s): Cleland, Kelly C.; Raymond, E.; Trussell, James; Cheng, L.A.; Zhu, H.P.

To refer to this page use:
Abstract: OBJECTIVE: To evaluate the existing data to estimate the rate of ectopic pregnancy among emergency contraceptive pill treatment failures. DATA SOURCES: Our initial reference list was generated from a 2008 Cochrane review of emergency contraception. In August 2009, we searched Biosys Previews, the Cochrane Database of Systematic Reviews, Medline, Global Health Database, Health Source: Popline, and Wanfang Data (a Chinese database). METHODS: This study included data from 136 studies, which followed a defined population of women treated one time with emergency contraceptive pills (either mifepristone or levonorgestrel) and in which the number and location of pregnancies were ascertained. RESULTS: Data from each article were abstracted independently by two reviewers. In the studies of mifepristone, 3 of 494 (0.6%) pregnancies were ectopic; in the levonorgestrel studies, 3 of 307 (1%) were ectopic. CONCLUSION: The rate of ectopic pregnancy when treatment with emergency contraceptive pills fails does not exceed the rate observed in the general population. Because emergency contraceptive pills are effective in lowering the risk of pregnancy, their use will reduce the chance that an act of intercourse will result in ectopic pregnancy. (Obstet Gynecol 2010; 115: 1263-6)
Publication Date: 2010
Citation: Cleland, K, Raymond, E, Trussell, J, Cheng, LA, Zhu, HP. (2010). Ectopic Pregnancy and Emergency Contraceptive Pills - A Systematic Review. Obstetrics and Gynecology, 115 (1263 - 1266. doi:10.1097/AOG.0b013e3181dd22ef
DOI: doi:10.1097/AOG.0b013e3181dd22ef
ISSN: 0029-7844
Pages: 1263 - 1266
Type of Material: Journal Article
Journal/Proceeding Title: Obstetrics and Gynecology
Version: Author's manuscript

Items in OAR@Princeton are protected by copyright, with all rights reserved, unless otherwise indicated.