Acute Infection Induces a Metastatic Niche: A Double Menace for Cancer Patients
Author(s): Smith, HA; Kang, Yibin
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http://arks.princeton.edu/ark:/88435/pr1xp6v34t| Abstract: | Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics. |
| Publication Date: | 6-Aug-2013 |
| DOI: | doi:10.1158/1078-0432.CCR-13-1524 |
| ISSN: | 1078-0432 |
| EISSN: | 1557-3265 |
| Type of Material: | Journal Article |
| Journal/Proceeding Title: | Clinical Cancer Research |
| Version: | Final published version. This is an open access article. |
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