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A high-stringency blueprint of the human proteome

Author(s): Adhikari, Subash; Nice, Edouard C; Deutsch, Eric W; Lane, Lydie; Omenn, Gilbert S; et al

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dc.contributor.authorAdhikari, Subash-
dc.contributor.authorNice, Edouard C-
dc.contributor.authorDeutsch, Eric W-
dc.contributor.authorLane, Lydie-
dc.contributor.authorOmenn, Gilbert S-
dc.contributor.authorPennington, Stephen R-
dc.contributor.authorPaik, Young-Ki-
dc.contributor.authorOverall, Christopher M-
dc.contributor.authorCorrales, Fernando J-
dc.contributor.authorCristea, Ileana M-
dc.contributor.authorVan Eyk, Jennifer E-
dc.contributor.authorUhlén, Mathias-
dc.contributor.authorLindskog, Cecilia-
dc.contributor.authorChan, Daniel W-
dc.contributor.authorBairoch, Amos-
dc.contributor.authorWaddington, James C-
dc.contributor.authorJustice, Joshua L-
dc.contributor.authorLaBaer, Joshua-
dc.contributor.authorRodriguez, Henry-
dc.contributor.authorHe, Fuchu-
dc.contributor.authorKostrzewa, Markus-
dc.contributor.authorPing, Peipei-
dc.contributor.authorGundry, Rebekah L-
dc.contributor.authorStewart, Peter-
dc.contributor.authorSrivastava, Sanjeeva-
dc.contributor.authorSrivastava, Sudhir-
dc.contributor.authorNogueira, Fabio CS-
dc.contributor.authorDomont, Gilberto B-
dc.contributor.authorVandenbrouck, Yves-
dc.contributor.authorLam, Maggie PY-
dc.contributor.authorWennersten, Sara-
dc.contributor.authorVizcaino, Juan Antonio-
dc.contributor.authorWilkins, Marc-
dc.contributor.authorSchwenk, Jochen M-
dc.contributor.authorLundberg, Emma-
dc.contributor.authorBandeira, Nuno-
dc.contributor.authorMarko-Varga, Gyorgy-
dc.contributor.authorWeintraub, Susan T-
dc.contributor.authorPineau, Charles-
dc.contributor.authorKusebauch, Ulrike-
dc.contributor.authorMoritz, Robert L-
dc.contributor.authorAhn, Seong Beom-
dc.contributor.authorPalmblad, Magnus-
dc.contributor.authorSnyder, Michael P-
dc.contributor.authorAebersold, Ruedi-
dc.contributor.authorBaker, Mark S-
dc.date.accessioned2022-01-25T14:52:28Z-
dc.date.available2022-01-25T14:52:28Z-
dc.date.issued2020-10-16en_US
dc.identifier.citationAdhikari, Subash, Nice, Edouard C, Deutsch, Eric W, Lane, Lydie, Omenn, Gilbert S, Pennington, Stephen R, Paik, Young-Ki, Overall, Christopher M, Corrales, Fernando J, Cristea, Ileana M, Van Eyk, Jennifer E, Uhlén, Mathias, Lindskog, Cecilia, Chan, Daniel W, Bairoch, Amos, Waddington, James C, Justice, Joshua L, LaBaer, Joshua, Rodriguez, Henry, He, Fuchu, Kostrzewa, Markus, Ping, Peipei, Gundry, Rebekah L, Stewart, Peter, Srivastava, Sanjeeva, Srivastava, Sudhir, Nogueira, Fabio CS, Domont, Gilberto B, Vandenbrouck, Yves, Lam, Maggie PY, Wennersten, Sara, Vizcaino, Juan Antonio, Wilkins, Marc, Schwenk, Jochen M, Lundberg, Emma, Bandeira, Nuno, Marko-Varga, Gyorgy, Weintraub, Susan T, Pineau, Charles, Kusebauch, Ulrike, Moritz, Robert L, Ahn, Seong Beom, Palmblad, Magnus, Snyder, Michael P, Aebersold, Ruedi, Baker, Mark S. (2020). A high-stringency blueprint of the human proteome.. Nature communications, 11 (1), 5301 - ?. doi:10.1038/s41467-020-19045-9en_US
dc.identifier.issn2041-1723-
dc.identifier.urihttp://arks.princeton.edu/ark:/88435/pr1mw28d5k-
dc.description.abstractThe Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP) in 2010, creating an international framework for global collaboration, data sharing, quality assurance and enhancing accurate annotation of the genome-encoded proteome. During the subsequent decade, the HPP established collaborations, developed guidelines and metrics, and undertook reanalysis of previously deposited community data, continuously increasing the coverage of the human proteome. On the occasion of the HPP's tenth anniversary, we here report a 90.4% complete high-stringency human proteome blueprint. This knowledge is essential for discerning molecular processes in health and disease, as we demonstrate by highlighting potential roles the human proteome plays in our understanding, diagnosis and treatment of cancers, cardiovascular and infectious diseases.en_US
dc.format.extent5301 - 5301en_US
dc.languageengen_US
dc.language.isoen_USen_US
dc.relation.ispartofNature Communicationsen_US
dc.rightsFinal published version. This is an open access article.en_US
dc.titleA high-stringency blueprint of the human proteomeen_US
dc.typeJournal Articleen_US
dc.identifier.doidoi:10.1038/s41467-020-19045-9-
dc.identifier.eissn2041-1723-
pu.type.symplectichttp://www.symplectic.co.uk/publications/atom-terms/1.0/journal-articleen_US

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