Skip to main content

Conserved regulators of cognitive aging: From worms to humans

Author(s): Arey, Rachel N; Murphy, Coleen T

To refer to this page use:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorArey, Rachel N-
dc.contributor.authorMurphy, Coleen T-
dc.identifier.citationArey, Rachel N, Murphy, Coleen T. (2017). Conserved regulators of cognitive aging: From worms to humans. Behavioural Brain Research, 322 (299 - 310). doi:10.1016/j.bbr.2016.06.035en_US
dc.description.abstractCognitive decline is a major deficit that arises with age in humans. While some research on the underlying causes of these problems can be done in humans, harnessing the strengths of small model systems, particularly those with well-studied longevity mutants, such as the nematode C. elegans, will accelerate progress. Here we review the approaches being used to study cognitive decline in model organisms and show how simple model systems allow the rapid discovery of conserved molecular mechanisms, which will eventually enable the development of therapeutics to slow cognitive aging.en_US
dc.format.extent299 - 310en_US
dc.relation.ispartofBehavioural Brain Researchen_US
dc.rightsAuthor's manuscripten_US
dc.titleConserved regulators of cognitive aging: From worms to humansen_US
dc.typeJournal Articleen_US

Files in This Item:
File Description SizeFormat 
Conserved_regulators_aging_worms_humans.pdf663.84 kBAdobe PDFView/Download

Items in OAR@Princeton are protected by copyright, with all rights reserved, unless otherwise indicated.