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Abstract: | Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies. |
Publication Date: | 1-Feb-2016 |
Electronic Publication Date: | 1-Feb-2016 |
Citation: | Shi, Cheng, Murphy, Coleen T. (2016). Feeding the germline. Genes & Development, 30 (3), 249 - 250. doi:10.1101/gad.276980.115 |
DOI: | doi:10.1101/gad.276980.115 |
ISSN: | 0890-9369 |
EISSN: | 1549-5477 |
Pages: | 249 - 250 |
Type of Material: | Journal Article |
Journal/Proceeding Title: | Genes & Development |
Version: | Final published version. This is an open access article. |
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