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How to draw the line in biomedical research

Author(s): Huang, Lisa; Rattner, Amir; Liu, Han; Nathans, Jeremy

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Abstract: The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.
Publication Date: 19-Mar-2013
Electronic Publication Date: 19-Mar-2013
Citation: Huang, Lisa, Amir Rattner, Han Liu, and Jeremy Nathans. "Tutorial: how to draw the line in biomedical research." Elife 2 (2013): e00638. doi:10.7554/eLife.00638
DOI: doi:10.7554/eLife.00638
EISSN: 2050-084X
Type of Material: Journal Article
Journal/Proceeding Title: eLife
Version: Final published version. This is an open access article.

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