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Planar cell polarity: global inputs establishing cellular asymmetry

Author(s): Aw, Wen Yih; Devenport, Danelle

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dc.contributor.authorAw, Wen Yih-
dc.contributor.authorDevenport, Danelle-
dc.date.accessioned2020-02-25T20:11:42Z-
dc.date.available2020-02-25T20:11:42Z-
dc.date.issued2018-02-01en_US
dc.identifier.citationAw, Wen Yih, Devenport, Danelle. (2017). Planar cell polarity: global inputs establishing cellular asymmetry. Current Opinion in Cell Biology, 44 (110 - 116. doi:10.1016/j.ceb.2016.08.002en_US
dc.identifier.issn0955-0674-
dc.identifier.urihttp://arks.princeton.edu/ark:/88435/pr13j4g-
dc.description.abstractMany tissues develop coordinated patterns of cell polarity that align with respect to the tissue axes. This phenomenon refers to planar cell polarity (PCP) and is controlled by multiple conserved PCP modules. A key feature of PCP proteins is their asymmetric localization within the tissue plane, whose orientation is guided by global directional cues. Here, we highlight current models and recent findings on the role of tissue-level gradients, local organizer signals, and mechanical forces in establishing the global patterns of PCP.en_US
dc.format.extent1 - 13en_US
dc.language.isoenen_US
dc.relation.ispartofCurrent Opinion in Cell Biologyen_US
dc.rightsAuthor's manuscripten_US
dc.titlePlanar cell polarity: global inputs establishing cellular asymmetryen_US
dc.typeJournal Articleen_US
dc.identifier.doidoi:10.1016/j.ceb.2016.08.002-
pu.type.symplectichttp://www.symplectic.co.uk/publications/atom-terms/1.0/journal-articleen_US

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