Mouse genomic screen reveals novel host regulator of metastasis.

Author(s): Celià-Terrassa, Toni; Kang, Yibin

Download

To refer to this page use: http://arks.princeton.edu/ark:/88435/pr10z0b

Full metadata record

DC Field	Value	Language
dc.contributor.author	Celià-Terrassa, Toni	-
dc.contributor.author	Kang, Yibin	-
dc.date.accessioned	2020-02-25T20:11:25Z	-
dc.date.available	2020-02-25T20:11:25Z	-
dc.date.issued	2017-02-16	en_US
dc.identifier.citation	Celià-Terrassa, Toni, Kang, Yibin. (2017). Mouse genomic screen reveals novel host regulator of metastasis.. Genome biology, 18 (1), 31 - ?. doi:10.1186/s13059-017-1170-x	en_US
dc.identifier.issn	1474-7596	-
dc.identifier.uri	http://arks.princeton.edu/ark:/88435/pr10z0b	-
dc.description.abstract	Tumor cells have to overcome challenges in the host tissue microenvironment to metastasize successfully to distant organs. In a recent Nature study, a genome-wide functional screen demonstrated that deficiency of the sphingosine-1-phoshate (S1P) transporter gene Spns2 in endothelium increased immune-mediated cell killing by T cells and natural killer (NK) cells, thereby suppressing metastatic colonization.	en_US
dc.format.extent	1 - 3	en_US
dc.language	eng	en_US
dc.language.iso	en	en_US
dc.relation.ispartof	Genome biology	en_US
dc.rights	Final published version. Article is made available in OAR by the publisher's permission or policy.	en_US
dc.title	Mouse genomic screen reveals novel host regulator of metastasis.	en_US
dc.type	Journal Article	en_US
dc.identifier.doi	doi:10.1186/s13059-017-1170-x	-
dc.identifier.eissn	1474-760X	-
pu.type.symplectic	http://www.symplectic.co.uk/publications/atom-terms/1.0/journal-article	en_US

Files in This Item:

File	Description	Size	Format
Mouse genomic screen reveals novel host regulator of metastasis.pdf		404.23 kB	Adobe PDF	View/Download