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FNTM: A server for predicting functional networks of tissues in mouse

Author(s): Goya, J; Wong, AK; Yao, V; Krishnan, A; Homilius, M; et al

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Abstract: Functional Networks of Tissues in Mouse (FNTM) provides biomedical researchers with tissue-specific predictions of functional relationships between proteins in the most widely used model organism for human disease, the laboratory mouse. Users can explore FNTM-predicted functional relationships for their tissues and genes of interest or examine gene function and interaction predictions across multiple tissues, all through an interactive, multi-tissue network browser. FNTM makes predictions based on integration of a variety of functional genomic data, including over 13 000 gene expression experiments, and prior knowledge of gene function. FNTM is an ideal starting point for clinical and translational researchers considering a mouse model for their disease of interest, researchers already working with mouse models who are interested in discovering new genes related to their pathways or phenotypes of interest, and biologists working with other organisms to explore the functional relationships of their genes of interest in specific mouse tissue contexts. FNTM predicts tissue-specific functional relationships in 200 tissues, does not require any registration or installation and is freely available for use at http://fntm.princeton.edu.
Publication Date: 1-Jul-2015
Electronic Publication Date: 1-Jul-2015
Citation: Goya, J, Wong, AK, Yao, V, Krishnan, A, Homilius, M, Troyanskaya, OG. (2015). FNTM: A server for predicting functional networks of tissues in mouse. Nucleic Acids Research, 43 (W182 - W187. doi:10.1093/nar/gkv443
DOI: doi:10.1093/nar/gkv443
Pages: W182 - W187
Type of Material: Journal Article
Journal/Proceeding Title: Nucleic Acids Research
Version: Final published version. Article is made available in OAR by the publisher's permission or policy.



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