Role of the Membrane for Mechanosensing by Tethered Channels

Author(s): Sabass, Benedikt; Stone, Howard A

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DC Field	Value	Language
dc.contributor.author	Sabass, Benedikt	-
dc.contributor.author	Stone, Howard A	-
dc.date.accessioned	2021-10-08T20:19:22Z	-
dc.date.available	2021-10-08T20:19:22Z	-
dc.date.issued	2016-06	en_US
dc.identifier.citation	Sabass, Benedikt, Stone, Howard A. (2016). Role of the Membrane for Mechanosensing by Tethered Channels. Physical Review Letters, 116 (25), 10.1103/PhysRevLett.116.258101	en_US
dc.identifier.issn	0031-9007	-
dc.identifier.uri	http://arks.princeton.edu/ark:/88435/pr1ts14	-
dc.description.abstract	Biologically important membrane channels are gated by force at attached tethers. Here, we generically characterize the nontrivial interplay of force, membrane tension, and channel deformations that can affect gating. A central finding is that minute conical channel deformation under force leads to significant energy release during opening. We also calculate channel-channel interactions and show that they can amplify the force sensitivity of tethered channels.	en_US
dc.language.iso	en_US	en_US
dc.relation.ispartof	Physical Review Letters	en_US
dc.rights	Author's manuscript	en_US
dc.title	Role of the Membrane for Mechanosensing by Tethered Channels	en_US
dc.type	Journal Article	en_US
dc.identifier.doi	doi:10.1103/PhysRevLett.116.258101	-
dc.date.eissued	2016-06-20	en_US
dc.identifier.eissn	1079-7114	-
pu.type.symplectic	http://www.symplectic.co.uk/publications/atom-terms/1.0/journal-article	en_US

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