Skip to main content

A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19

Author(s): Rajil, Navid; Sokolov, Alexei; Yi, Zhenhuan; Adams, Garry; Agarwal, Girish; et al

To refer to this page use:
Abstract: Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.
Publication Date: 29-Sep-2020
Citation: Rajil, Navid, Sokolov, Alexei, Yi, Zhenhuan, Adams, Garry, Agarwal, Girish, Belousov, Vsevolod, Brick, Robert, Chapin, Kimberly, Cirillo, Jeffrey, Deckert, Volker, Delfan, Sahar, Esmaeili, Shahriar, Fernández-González, Alma, Fry, Edward, Han, Zehua, Hemmer, Philip, Kattawar, George, Kim, Moochan, Lee, Ming-Che, Lu, Chao-Yang, Mogford, Jon, Neuman, Benjamin, Pan, Jian-Wei, Peng, Tao, Poor, Vincent, Scully, Steven, Shih, Yanhua, Suckewer, Szymon, Svidzinsky, Anatoly, Verhoef, Aart, Wang, Dawei, Wang, Kai, Yang, Lan, Zheltikov, Aleksei, Zhu, Shiyao, Zubairy, Suhail, Scully, Marlan. (2020). A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19. Nanophotonics, 10 (1), 235 - 246. doi:10.1515/nanoph-2020-0357
DOI: doi:10.1515/nanoph-2020-0357
ISSN: 2192-8606
EISSN: 2192-8614
Pages: 235 - 246
Type of Material: Journal Article
Journal/Proceeding Title: Nanophotonics
Version: Final published version. This is an open access article.

Items in OAR@Princeton are protected by copyright, with all rights reserved, unless otherwise indicated.